Journal article
Personality traits as mediators of the relationship between childhood trauma and depression severity in bipolar disorder: A structural equation model
AL Wrobel, SE Russell, A Jayasinghe, BE Kavanagh, M Lotfaliany, A Turner, OM Dean, SM Cotton, C Diaz-Byrd, AK Yocum, ER Duval, TJ Ehrlich, DF Marshall, M Berk, MG McInnis
Australian and New Zealand Journal of Psychiatry | SAGE PUBLICATIONS LTD | Published : 2023
Abstract
Background: Childhood trauma is negatively associated with depression severity in bipolar disorder; however, the underlying mechanisms remain unclear. We investigated whether personality traits (neuroticism, extraversion, openness, agreeableness, conscientiousness) mediate the relationship between childhood trauma and the severity of bipolar depression. Methods: Data from 209 individuals with bipolar disorder recruited for the Prechter Longitudinal Study of Bipolar Disorder were analysed. Using structural equation modelling, we examined the direct and indirect associations between childhood trauma (Childhood Trauma Questionnaire) and depression severity (Hamilton Depression Rating Scale) – w..
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Awarded by National Institutes of Health
Funding Acknowledgements
The author(s) disclosed receipt of the following financial support for the research, authorship and/or publication of this article: A.L.W. was supported by a Deakin University Centre of Research Excellence in Psychiatric Treatment Postgraduate Research Scholarship. S.E.R. was supported by an Australian Government Research Training Programme Scholarship. A.J. was supported by a Deakin University Research Training Programme Scholarship. M.L. was supported by an Alfred Deakin Post-Doctorate Research Fellowship (ADPRF). O.M.D. was supported by an NHMRC RD Wright Biomedical Career Development Fellowship (APP1145634). S.M.C. was supported by a NHMRC Senior Research Fellowship (APP1136344). E.R.D. was supported by the National Institutes of Mental Health (K23MH109762). M.B. was supported by a NHMRC Senior Principal Research Fellowship (APP1156072). Data collection for the Prechter Longitudinal Study of Bipolar Disorder was supported by Heinz C Prechter Bipolar Programme, the Richard Tam Foundation, the Department of Psychiatry and the Eisenberg Family Depression Centre at the University of Michigan.